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##  303 results 

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### 2024

Hsieh A, Ganesh S, Kula T, Irshad M, Ferenczi EA, Wang W, Chen Y-C, Hu S-H, Li Z, Joshi S, et al. [Widespread Neuroanatomical Integration and Distinct Electrophysiological Properties of Glioma-Innervating Neurons](/publications/widespread-neuroanatomical-integration-and-distinct-electrophysiological). bioRxiv. 2024. doi:10.1101/2024.08.25.609573



 

 

Hsieh A, Ganesh S, Kula T, Irshad M, Ferenczi EA, Wang W, Chen Y-C, Hu S-H, Li Z, Joshi S, et al. [Widespread Neuroanatomical Integration and Distinct Electrophysiological Properties of Glioma-Innervating Neurons](/publications/widespread-neuroanatomical-integration-and-distinct-electrophysiological). bioRxiv. 2024. doi:10.1101/2024.08.25.609573



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 UNLABELLED: Gliomas are the most common malignant primary brain tumors and are often associated with severe neurological deficits and mortality. Unlike many cancers, gliomas rarely metastasize outside the brain, indicating a possible dependency on unique... 

 

 

 

Hochbaum D, Hulshof L, Urke A, Wang W, Dubinsky A, Farnsworth H, Hakim R, Lin S, Kleinberg G, Robertson K, et al. [Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration](/publications/thyroid-hormone-remodels-cortex-coordinate-body-wide-metabolism-and). Cell. 2024. doi:10.1016/j.cell.2024.07.041



 

 

Hochbaum D, Hulshof L, Urke A, Wang W, Dubinsky A, Farnsworth H, Hakim R, Lin S, Kleinberg G, Robertson K, et al. [Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration](/publications/thyroid-hormone-remodels-cortex-coordinate-body-wide-metabolism-and). Cell. 2024. doi:10.1016/j.cell.2024.07.041



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Animals adapt to environmental conditions by modifying the function of their internal organs, including the brain. To be adaptive, alterations in behavior must be coordinated with the functional state of organs throughout the body. Here, we find that... 

 

 

 

Nguyen N, Lutas A, Amsalem O, Fernando J, Ahn AY-E, Hakim R, Vergara J, McMahon J, Dimidschstein J, Sabatini B, et al. [Cortical reactivations predict future sensory responses](/publications/cortical-reactivations-predict-future-sensory-responses). Nature. 2024;625(7993):110–118. doi:10.1038/s41586-023-06810-1



 

 

Nguyen N, Lutas A, Amsalem O, Fernando J, Ahn AY-E, Hakim R, Vergara J, McMahon J, Dimidschstein J, Sabatini B, et al. [Cortical reactivations predict future sensory responses](/publications/cortical-reactivations-predict-future-sensory-responses). Nature. 2024;625(7993):110–118. doi:10.1038/s41586-023-06810-1



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Many theories of offline memory consolidation posit that the pattern of neurons activated during a salient sensory experience will be faithfully reactivated, thereby stabilizing the pattern1,2. However, sensory-evoked patterns are not stable but, instead... 

 

 

 

Lawton R, Sabatini B, Hochbaum D. [Longevity, demographic characteristics, and socio-economic status are linked to triiodothyronine levels in the general population](/publications/longevity-demographic-characteristics-and-socio-economic-status-are-linked). Proc Natl Acad Sci U S A. 2024;121(2):e2308652121. doi:10.1073/pnas.2308652121



 

 

Lawton R, Sabatini B, Hochbaum D. [Longevity, demographic characteristics, and socio-economic status are linked to triiodothyronine levels in the general population](/publications/longevity-demographic-characteristics-and-socio-economic-status-are-linked). Proc Natl Acad Sci U S A. 2024;121(2):e2308652121. doi:10.1073/pnas.2308652121



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 The hypothalamic-pituitary-thyroid (HPT) axis is fundamental to human biology, exerting central control over energy expenditure and body temperature. However, the consequences of normal physiologic HPT-axis variation in populations without diagnosed... 

 

 

 

 



### 2023

Reinhold K, Iadarola M, Tang S, Kuwamoto W, Sun S, Hakim R, Zimmer J, Wang W, Sabatini B. [Striatum supports fast learning but not memory recall](/publications/striatum-supports-fast-learning-not-memory-recall). bioRxiv. 2023. doi:10.1101/2023.11.08.566333



 

 

Reinhold K, Iadarola M, Tang S, Kuwamoto W, Sun S, Hakim R, Zimmer J, Wang W, Sabatini B. [Striatum supports fast learning but not memory recall](/publications/striatum-supports-fast-learning-not-memory-recall). bioRxiv. 2023. doi:10.1101/2023.11.08.566333



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Animals learn to carry out motor actions in specific sensory contexts to achieve goals. The striatum has been implicated in producing sensory-motor associations, yet its contribution to memory formation or recall is not clear. To investigate the... 

 

 

 

Tilden E, Maduskar A, Oldenborg A, Sabatini B, Chen Y. [A Cre-dependent reporter mouse for quantitative real-time imaging of Protein Kinase A activity dynamics](/publications/cre-dependent-reporter-mouse-quantitative-real-time-imaging-protein-kinase). bioRxiv. 2023. doi:10.1101/2023.10.31.565028



 

 

Tilden E, Maduskar A, Oldenborg A, Sabatini B, Chen Y. [A Cre-dependent reporter mouse for quantitative real-time imaging of Protein Kinase A activity dynamics](/publications/cre-dependent-reporter-mouse-quantitative-real-time-imaging-protein-kinase). bioRxiv. 2023. doi:10.1101/2023.10.31.565028



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Intracellular signaling dynamics play a crucial role in cell function. Protein kinase A (PKA) is a key signaling molecule that has diverse functions, from regulating metabolism and brain activity to guiding development and cancer progression. We... 

 

 

 

Wallace M, Sabatini B. [Synaptic and circuit functions of multitransmitter neurons in the mammalian brain](/publications/synaptic-and-circuit-functions-multitransmitter-neurons-mammalian-brain). Neuron. 2023;111(19):2969–2983. doi:10.1016/j.neuron.2023.06.003



 

 

Wallace M, Sabatini B. [Synaptic and circuit functions of multitransmitter neurons in the mammalian brain](/publications/synaptic-and-circuit-functions-multitransmitter-neurons-mammalian-brain). Neuron. 2023;111(19):2969–2983. doi:10.1016/j.neuron.2023.06.003



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Neurons in the mammalian brain are not limited to releasing a single neurotransmitter but often release multiple neurotransmitters onto postsynaptic cells. Here, we review recent findings of multitransmitter neurons found throughout the mammalian central... 

 

 

 

Chantranupong L, Beron C, Zimmer J, Wen M, Wang W, Sabatini B. [Dopamine and glutamate regulate striatal acetylcholine in decision-making](/publications/dopamine-and-glutamate-regulate-striatal-acetylcholine-decision-making). Nature. 2023;621(7979):577–585. doi:10.1038/s41586-023-06492-9



 

 

Chantranupong L, Beron C, Zimmer J, Wen M, Wang W, Sabatini B. [Dopamine and glutamate regulate striatal acetylcholine in decision-making](/publications/dopamine-and-glutamate-regulate-striatal-acetylcholine-decision-making). Nature. 2023;621(7979):577–585. doi:10.1038/s41586-023-06492-9



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Striatal dopamine and acetylcholine are essential for the selection and reinforcement of motor actions and decision-making1. In vitro studies have revealed an intrastriatal circuit in which acetylcholine, released by cholinergic interneurons (CINs)... 

 

 

 

Hochbaum D, Dubinsky A, Farnsworth H, Hulshof L, Kleinberg G, Urke A, Wang W, Hakim R, Robertson K, Park C, et al. [Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive](/publications/thyroid-hormone-rewires-cortical-circuits-coordinate-body-wide-metabolism). bioRxiv. 2023. doi:10.1101/2023.08.10.552874



 

 

Hochbaum D, Dubinsky A, Farnsworth H, Hulshof L, Kleinberg G, Urke A, Wang W, Hakim R, Robertson K, Park C, et al. [Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive](/publications/thyroid-hormone-rewires-cortical-circuits-coordinate-body-wide-metabolism). bioRxiv. 2023. doi:10.1101/2023.08.10.552874



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Animals adapt to varying environmental conditions by modifying the function of their internal organs, including the brain. To be adaptive, alterations in behavior must be coordinated with the functional state of organs throughout the body. Here we find... 

 

 

 

Lawton R, Sabatini B, Hochbaum D. [Sub-clinical triiodothyronine levels predict health, demographic, and socioeconomic outcomes](/publications/sub-clinical-triiodothyronine-levels-predict-health-demographic-and). bioRxiv. 2023. doi:10.1101/2023.03.09.531775



 

 

Lawton R, Sabatini B, Hochbaum D. [Sub-clinical triiodothyronine levels predict health, demographic, and socioeconomic outcomes](/publications/sub-clinical-triiodothyronine-levels-predict-health-demographic-and). bioRxiv. 2023. doi:10.1101/2023.03.09.531775



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 The Hypothalamic-Pituitary-Thyroid (HPT) axis is fundamental to human biology, exerting central control over energy expenditure, metabolic rate, and body temperature. However, the consequences of "normal" physiologic HPT-axis variation in non-clinical... 

 

 

 

Pollina E, Gilliam D, Landau A, Lin C, Pajarillo N, Davis C, Harmin D, Yap E-L, Vogel I, Griffith E, et al. [A NPAS4-NuA4 complex couples synaptic activity to DNA repair](/publications/npas4-nua4-complex-couples-synaptic-activity-dna-repair). Nature. 2023;614(7949):732–741. doi:10.1038/s41586-023-05711-7



 

 

Pollina E, Gilliam D, Landau A, Lin C, Pajarillo N, Davis C, Harmin D, Yap E-L, Vogel I, Griffith E, et al. [A NPAS4-NuA4 complex couples synaptic activity to DNA repair](/publications/npas4-nua4-complex-couples-synaptic-activity-dna-repair). Nature. 2023;614(7949):732–741. doi:10.1038/s41586-023-05711-7



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Neuronal activity is crucial for adaptive circuit remodelling but poses an inherent risk to the stability of the genome across the long lifespan of postmitotic neurons1-5. Whether neurons have acquired specialized genome protection mechanisms that enable... 

 

 

 

Markowitz J, Gillis W, Jay M, Wood J, Harris R, Cieszkowski R, Scott R, Brann D, Koveal D, Kula T, et al. [Spontaneous behaviour is structured by reinforcement without explicit reward](/publications/spontaneous-behaviour-structured-reinforcement-without-explicit-reward). Nature. 2023;614(7946):108–117. doi:10.1038/s41586-022-05611-2



 

 

Markowitz J, Gillis W, Jay M, Wood J, Harris R, Cieszkowski R, Scott R, Brann D, Koveal D, Kula T, et al. [Spontaneous behaviour is structured by reinforcement without explicit reward](/publications/spontaneous-behaviour-structured-reinforcement-without-explicit-reward). Nature. 2023;614(7946):108–117. doi:10.1038/s41586-022-05611-2



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Spontaneous animal behaviour is built from action modules that are concatenated by the brain into sequences1,2. However, the neural mechanisms that guide the composition of naturalistic, self-motivated behaviour remain unknown. Here we show that dopamine... 

 

 

 

 



 

 

 

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